Fever And Chills
patients may experience chills and a high fever as a side effect of metformin. A fever is a temperature above 100.4 degrees Fahrenheit. A high fever is when the temperature of a patient is greater than 103.1 degrees Fahrenheit. A person can feel extremely cold, even if their body temperature is normal. Chills can cause patients to shiver, and their skin may feel clammy. Metformin patients who experience a fever and chills should contact their doctor right away. Chills can be a sign that lactic acidosis is a rare but severe side effect.